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Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells

The Rho/ROCK pathway is a promising therapeutic target in neurodegenerative and neurotraumatic diseases. Pharmacological inhibition of various pathway members has been shown to promote neuronal regeneration and survival. However, because pharmacological inhibitors are inherently limited in their spe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Koch, Jan Christoph, Tönges, Lars, Michel, Uwe, Bähr, Mathias, Lingor, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155783/
https://ncbi.nlm.nih.gov/pubmed/25249936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00273
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