Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes

AIM: Our objective was to describe the association between voriconazole concentrations and CYP2C19 diplotypes in pediatric cancer patients, including children homozygous for the CYP2C19*17 gain-of-function allele. MATERIALS & METHODS: A linear mixed effect model compared voriconazole dose-correc...

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Detaylı Bibliyografya
Asıl Yazarlar: Hicks, J Kevin, Crews, Kristine R, Flynn, Patricia, Haidar, Cyrine E, Daniels, Calvin C, Yang, Wenjian, Panetta, John C, Pei, Deqing, Scott, Jeffrey R, Molinelli, Alejandro R, Broeckel, Ulrich, Bhojwani, Deepa, Evans, William E, Relling, Mary V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155516/
https://ncbi.nlm.nih.gov/pubmed/25084200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.53
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