Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes

AIM: Our objective was to describe the association between voriconazole concentrations and CYP2C19 diplotypes in pediatric cancer patients, including children homozygous for the CYP2C19*17 gain-of-function allele. MATERIALS & METHODS: A linear mixed effect model compared voriconazole dose-correc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hicks, J Kevin, Crews, Kristine R, Flynn, Patricia, Haidar, Cyrine E, Daniels, Calvin C, Yang, Wenjian, Panetta, John C, Pei, Deqing, Scott, Jeffrey R, Molinelli, Alejandro R, Broeckel, Ulrich, Bhojwani, Deepa, Evans, William E, Relling, Mary V
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155516/
https://ncbi.nlm.nih.gov/pubmed/25084200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.14.53
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