Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

BACKGROUND: Minocycline, a semi-synthetic tetracycline antibiotic, is an effective neuroprotective agent in animal models of cerebral ischemia when given in high doses intraperitoneally. The aim of this study was to determine if minocycline was effective at reducing infarct size in a Temporary Middl...

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Main Authors: Xu, Lin, Fagan, Susan C, Waller, Jennifer L, Edwards, David, Borlongan, Cesar V, Zheng, Jianqing, Hill, William D, Feuerstein, Giora, Hess, David C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2004
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC415551/
https://ncbi.nlm.nih.gov/pubmed/15109399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-4-7
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