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The neuroprotective effects of pregabalin after cerebral ischemia by occlusion of the middle cerebral artery in rats
Activation of presynaptic voltage-gated calcium channels and glutamate release serves a central role in neuronal necrosis after cerebral ischemia. Pregabalin binds to the α2-δ subunit of voltage-gated calcium channels and results in reduced glutamate release. The aim of the current study was to eval...
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| Publicat a: | Exp Ther Med |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7792490/ https://ncbi.nlm.nih.gov/pubmed/33456532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9596 |
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