Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke

BACKGROUND: Minocycline, a second-generation tetracycline with anti-inflammatory and anti-apoptotic properties, has been shown to promote therapeutic benefits in experimental stroke. However, equally compelling evidence demonstrates that the drug exerts variable and even detrimental effects in many...

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Autori principali: Matsukawa, Noriyuki, Yasuhara, Takao, Hara, Koichi, Xu, Lin, Maki, Mina, Yu, Guolong, Kaneko, Yuji, Ojika, Kosei, Hess, David C, Borlongan, Cesar V
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762982/
https://ncbi.nlm.nih.gov/pubmed/19807907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-126
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