Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

BACKGROUND: Minocycline, a semi-synthetic tetracycline antibiotic, is an effective neuroprotective agent in animal models of cerebral ischemia when given in high doses intraperitoneally. The aim of this study was to determine if minocycline was effective at reducing infarct size in a Temporary Middl...

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Detalhes bibliográficos
Main Authors: Xu, Lin, Fagan, Susan C, Waller, Jennifer L, Edwards, David, Borlongan, Cesar V, Zheng, Jianqing, Hill, William D, Feuerstein, Giora, Hess, David C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415551/
https://ncbi.nlm.nih.gov/pubmed/15109399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-4-7
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