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Application of Reverse Genetics for Producing Attenuated Vaccine Strains against Highly Pathogenic Avian Influenza Viruses

In this study, reverse genetics was applied to produce vaccine candidate strains against highly pathogenic avian influenza viruses (HPAIVs) of the H5N1 subtype. The H5 subtype vaccine strains were generated by a reverse genetics method in a biosafety level 2 facility. The strain contained the HA gen...

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Bibliografiske detaljer
Main Authors: UCHIDA, Yuko, TAKEMAE, Nobuhiro, SAITO, Takehiko
Format: Artigo
Sprog:Inglês
Udgivet: The Japanese Society of Veterinary Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155191/
https://ncbi.nlm.nih.gov/pubmed/24805906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0620
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