Amino Acid Substitutions in PB1 of Avian Influenza Viruses Influence Pathogenicity and Transmissibility in Chickens

Amino acid substitutions were introduced into avian influenza virus PB1 in order to characterize the interaction between polymerase activity and pathogenicity. Previously, we used recombinant viruses containing the hemagglutinin (HA) and neuraminidase (NA) genes from the highly pathogenic avian infl...

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Bibliografiska uppgifter
Huvudupphovsmän: Suzuki, Yasushi, Uchida, Yuko, Tanikawa, Taichiro, Maeda, Naohiro, Takemae, Nobuhiro, Saito, Takehiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178826/
https://ncbi.nlm.nih.gov/pubmed/25031333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-14
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