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Amino Acid Substitutions in PB1 of Avian Influenza Viruses Influence Pathogenicity and Transmissibility in Chickens

Amino acid substitutions were introduced into avian influenza virus PB1 in order to characterize the interaction between polymerase activity and pathogenicity. Previously, we used recombinant viruses containing the hemagglutinin (HA) and neuraminidase (NA) genes from the highly pathogenic avian infl...

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書誌詳細
主要な著者: Suzuki, Yasushi, Uchida, Yuko, Tanikawa, Taichiro, Maeda, Naohiro, Takemae, Nobuhiro, Saito, Takehiko
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178826/
https://ncbi.nlm.nih.gov/pubmed/25031333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-14
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