Chicken MDA5 Senses Short Double-Stranded RNA with Implications for Antiviral Response against Avian Influenza Viruses in Chicken

Mammalian melanoma differentiation-associated gene-5 (MDA5) and retinoic acid-inducible gene-I (RIG-I) selectively sense double-stranded RNA (dsRNA) according to length, as well as various RNA viruses to induce an antiviral response. RIG-I, which plays a predominant role in the induction of antivira...

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Veröffentlicht in:J Innate Immun
Hauptverfasser: Hayashi, Tsuyoshi, Watanabe, Chiaki, Suzuki, Yasushi, Tanikawa, Taichiro, Uchida, Yuko, Saito, Takehiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741575/
https://ncbi.nlm.nih.gov/pubmed/23860388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351583
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