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Application of Reverse Genetics for Producing Attenuated Vaccine Strains against Highly Pathogenic Avian Influenza Viruses

In this study, reverse genetics was applied to produce vaccine candidate strains against highly pathogenic avian influenza viruses (HPAIVs) of the H5N1 subtype. The H5 subtype vaccine strains were generated by a reverse genetics method in a biosafety level 2 facility. The strain contained the HA gen...

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Bibliografske podrobnosti
Main Authors: UCHIDA, Yuko, TAKEMAE, Nobuhiro, SAITO, Takehiko
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Veterinary Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155191/
https://ncbi.nlm.nih.gov/pubmed/24805906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0620
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