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Application of Reverse Genetics for Producing Attenuated Vaccine Strains against Highly Pathogenic Avian Influenza Viruses

In this study, reverse genetics was applied to produce vaccine candidate strains against highly pathogenic avian influenza viruses (HPAIVs) of the H5N1 subtype. The H5 subtype vaccine strains were generated by a reverse genetics method in a biosafety level 2 facility. The strain contained the HA gen...

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Autores principales: UCHIDA, Yuko, TAKEMAE, Nobuhiro, SAITO, Takehiko
Formato: Artigo
Lenguaje:Inglês
Publicado: The Japanese Society of Veterinary Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155191/
https://ncbi.nlm.nih.gov/pubmed/24805906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.13-0620
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