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An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

Embryonic Stem cells derived from the epiblast tissue of the mammalian blastocyst retain the capability to differentiate into any adult cell type and are able to self-renew indefinitely under appropriate culture conditions. Despite the large amount of knowledge that we have accumulated to date about...

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Detalhes bibliográficos
Main Authors: Turner, David A., Trott, Jamie, Hayward, Penelope, Rué, Pau, Martinez Arias, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154298/
https://ncbi.nlm.nih.gov/pubmed/24950969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148409
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