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A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells
Pluripotency in embryonic stem cells is maintained through the activity of a small set of transcription factors centred around Oct4 and Nanog, which control the expression of ‘self-renewal’ and ‘differentiation’ genes. Here, we combine single-cell quantitative immunofluorescence microscopy and gene...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817399/ https://ncbi.nlm.nih.gov/pubmed/24104477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.49 |
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