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Chronic hypoxia limits H(2)O(2)-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle
Our laboratory shows that acid-sensing ion channel 1 (ASIC1) contributes to the development of hypoxic pulmonary hypertension by augmenting store-operated Ca(2+) entry (SOCE) that is associated with enhanced agonist-induced vasoconstriction and arterial remodeling. However, this enhanced Ca(2+) infl...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154254/ https://ncbi.nlm.nih.gov/pubmed/24993130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00095.2014 |
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