Chronic hypoxia limits H(2)O(2)-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle

Our laboratory shows that acid-sensing ion channel 1 (ASIC1) contributes to the development of hypoxic pulmonary hypertension by augmenting store-operated Ca(2+) entry (SOCE) that is associated with enhanced agonist-induced vasoconstriction and arterial remodeling. However, this enhanced Ca(2+) infl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Plomaritas, Danielle R., Herbert, Lindsay M., Yellowhair, Tracylyn R., Resta, Thomas C., Gonzalez Bosc, Laura V., Walker, Benjimen R., Jernigan, Nikki L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154254/
https://ncbi.nlm.nih.gov/pubmed/24993130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00095.2014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados