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Role of ASIC1 in the development of chronic hypoxia-induced pulmonary hypertension

Chronic hypoxia (CH) associated with respiratory disease results in elevated pulmonary vascular intracellular Ca(2+) concentration, which elicits enhanced vasoconstriction and promotes vascular arterial remodeling and thus has important implications in the development of pulmonary hypertension (PH)....

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Autors principals: Nitta, Carlos H., Osmond, David A., Herbert, Lindsay M., Beasley, Britta F., Resta, Thomas C., Walker, Benjimen R., Jernigan, Nikki L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920158/
https://ncbi.nlm.nih.gov/pubmed/24186095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00269.2013
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