PICK1/calcineurin suppress ASIC1-mediated Ca(2+) entry in rat pulmonary arterial smooth muscle cells

Acid-sensing ion channel 1 (ASIC1) contributes to Ca(2+) influx and contraction in pulmonary arterial smooth muscle cells (PASMC). ASIC1 binds the PDZ (PSD-95/Dlg/ZO-1) domain of the protein interacting with C kinase 1 (PICK1), and this interaction is important for the subcellular localization and/o...

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izdano v:Am J Physiol Cell Physiol
Main Authors: Herbert, Lindsay M., Nitta, Carlos H., Yellowhair, Tracylyn R., Browning, Carly, Gonzalez Bosc, Laura V., Resta, Thomas C., Jernigan, Nikki L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971828/
https://ncbi.nlm.nih.gov/pubmed/26702130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00091.2015
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