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Targeting the undruggable: Advances and obstacles in current RNAi therapy

RNA interference (RNAi) therapeutics represents a rapidly emerging platform for personalized cancer treatment. Recent advances in delivery, target selection, and safety of RNAi cancer therapy provide unprecedented opportunities for clinical translation. Here, we discuss these advances and present st...

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Detalhes bibliográficos
Main Authors: Wu, Sherry Y., Lopez-Berestein, Gabriel, Calin, George A., Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154139/
https://ncbi.nlm.nih.gov/pubmed/24920658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008362
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