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Targeting the undruggable: Advances and obstacles in current RNAi therapy

RNA interference (RNAi) therapeutics represents a rapidly emerging platform for personalized cancer treatment. Recent advances in delivery, target selection, and safety of RNAi cancer therapy provide unprecedented opportunities for clinical translation. Here, we discuss these advances and present st...

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Detalles Bibliográficos
Autores principales: Wu, Sherry Y., Lopez-Berestein, Gabriel, Calin, George A., Sood, Anil K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154139/
https://ncbi.nlm.nih.gov/pubmed/24920658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008362
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