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ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease

Polycystic kidney disease (PKD) is a common genetic disorder leading to cyst formation in the kidneys and other organs that ultimately results in kidney failure and death. Currently, there is no therapy for slowing down or stopping the progression of PKD. In this study, we identified the disintegrin...

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Detalhes bibliográficos
Main Authors: Beck Gooz, Monika, Maldonado, Eduardo N., Dang, Yujing, Amria, May Y., Higashiyama, Shigeki, Abboud, Hanna E., Lemasters, John J., Bell, P. Darwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154111/
https://ncbi.nlm.nih.gov/pubmed/24899059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00218.2014
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