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A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by α5β1 Integrin in Kidney Mesangial Cells

BACKGROUND: The disintegrin and metalloenzyme ADAM17 participates in numerous inflammatory and proliferative diseases, and its pathophysiological role was implicated in kidney fibrosis, polycystic kidney disease and other chronic kidney diseases. At present, we have little understanding how the enzy...

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Detalhes bibliográficos
Main Authors: Gooz, Pal, Dang, Yujing, Higashiyama, Shigeki, Twal, Waleed O., Haycraft, Courtney J., Gooz, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297637/
https://ncbi.nlm.nih.gov/pubmed/22413019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033350
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