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Inhibition of Aerobic Glycolysis Attenuates Disease Progression in Polycystic Kidney Disease
Dysregulated signaling cascades alter energy metabolism and promote cell proliferation and cyst expansion in polycystic kidney disease (PKD). Here we tested whether metabolic reprogramming towards aerobic glycolysis (“Warburg effect”) plays a pathogenic role in male heterozygous Han:SPRD rats (Cy/+)...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4708993/ https://ncbi.nlm.nih.gov/pubmed/26752072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146654 |
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