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A systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening

A goal of the Tox21 program is to transit toxicity testing from traditional in vivo models to in vitro assays that assess how chemicals affect cellular responses and toxicity pathways. A critical contribution of the NIH Chemical Genomics center (NCGC) to the Tox21 program is the implementation of a...

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Hlavní autoři: Attene-Ramos, Matias S., Huang, Ruili, Sakamuru, Srilatha, Witt, Kristine L., Beeson, Gyda C., Shou, Louie, Schnellmann, Rick G., Beeson, Craig C., Tice, Raymond R., Austin, Christopher P., Xia, Menghang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154066/
https://ncbi.nlm.nih.gov/pubmed/23895456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx4001754
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