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Phase I study of the combination of temsirolimus and pazopanib in advanced solid tumors
OBJECTIVES: Inhibition of either vascular endothelial growth factor receptor (VEGFR) or mammalian target of rapamycin (mTOR) signaling improves outcomes in patients with several advanced solid tumors. We conducted a phase I trial of temsirolimus with pazopanib to investigate the feasibility of simul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153755/ https://ncbi.nlm.nih.gov/pubmed/23698253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e3283618b7b |
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