A Phase I study of pazopanib in combination with gemcitabine in patients with advanced solid tumors

PURPOSE: Pazopanib plus gemcitabine combination therapy was explored in patients with advanced solid tumors. METHODS: In a modified 3 + 3 enrollment scheme, oral once-daily pazopanib was administered with intravenous gemcitabine (Days 1 and 8, 21-day cycles). Three protocol-specified dose levels wer...

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Main Authors: Plummer, Ruth, Madi, Ayman, Jeffels, Melinda, Richly, Heike, Nokay, Bahar, Rubin, Stephen, Ball, Howard A., Weller, Steve, Botbyl, Jeffrey, Gibson, Diana M., Scheulen, Max E.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535414/
https://ncbi.nlm.nih.gov/pubmed/23064954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1982-z
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