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A Pentasymmetric Open Channel Blocker for Cys-Loop Receptor Channels
γ-Aminobutyric acid type A receptors (GABA(A) receptors) are chloride ion channels composed of five subunits, mediating fast synaptic and tonic inhibition in the mammalian brain. These receptors show near five-fold symmetry that is most pronounced in the second trans-membrane domain M2 lining the Cl...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153658/ https://ncbi.nlm.nih.gov/pubmed/25184303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106688 |
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