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A Pentasymmetric Open Channel Blocker for Cys-Loop Receptor Channels
γ-Aminobutyric acid type A receptors (GABA(A) receptors) are chloride ion channels composed of five subunits, mediating fast synaptic and tonic inhibition in the mammalian brain. These receptors show near five-fold symmetry that is most pronounced in the second trans-membrane domain M2 lining the Cl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153658/ https://ncbi.nlm.nih.gov/pubmed/25184303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106688 |
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