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Cys-Loop Receptor Channel Blockers Also Block GLIC

The Gloeobacter ligand-gated ion channel (GLIC) is a bacterial homolog of vertebrate Cys-loop ligand-gated ion channels. Its pore-lining region in particular has a high sequence homology to these related proteins. Here we use electrophysiology to examine a range of compounds that block the channels...

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Detalhes bibliográficos
Main Authors: Alqazzaz, Mona, Thompson, Andrew J., Price, Kerry L., Breitinger, Hans-Georg, Lummis, Sarah C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244065/
https://ncbi.nlm.nih.gov/pubmed/22208189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.10.055
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