Using Positron Emission Tomography to Study Transporter-Mediated Drug–Drug Interactions in Tissues

Drug disposition is highly regulated by membrane transporters. Some transporter-mediated drug–drug interactions (DDIs) may not manifest themselves in changes in systemic exposure but rather in changes in tissue exposure of drugs. To better assess the impact of transporter-mediated DDIs in tissues, p...

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Detalhes bibliográficos
Main Authors: Wulkersdorfer, B, Wanek, T, Bauer, M, Zeitlinger, M, Müller, M, Langer, O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153445/
https://ncbi.nlm.nih.gov/pubmed/24682030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2014.70
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