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An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts
A central goal of regenerative medicine is to generate transplantable organs from cells derived or expanded in vitro. Although numerous studies have demonstrated production of defined cell-types in vitro(1), creation of a fully intact organ has not been reported. The transcription factor Forkhead bo...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4153409/ https://ncbi.nlm.nih.gov/pubmed/25150981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3023 |
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