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Increased sensitivity of glioma cells to 5-fluorocytosine following photo-chemical internalization enhanced nonviral transfection of the cytosine deaminase suicide gene

Despite advances in surgery, chemotherapy and radiotherapy, the outcomes of patients with GBM have not significantly improved. Tumor recurrence in the resection margins occurs in more than 80 % of cases indicating aggressive treatment modalities, such as gene therapy are warranted. We have examined...

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Detalhes bibliográficos
Main Authors: Wang, Frederick, Zamora, Genesis, Sun, Chung-Ho, Trinidad, Anthony, Chun, Changho, Kwon, Young Jik, Berg, Kristian, Madsen, Steen J., Hirschberg, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153358/
https://ncbi.nlm.nih.gov/pubmed/24610460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-014-1410-9
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