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Wnt Signaling Controls the Specification of Definitive and Primitive Hematopoiesis From Human Pluripotent Stem Cells

Efforts to derive hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) are complicated by the fact that embryonic hematopoiesis consists of two programs, primitive and definitive, that differ in developmental potential. As only definitive hematopoiesis generates HSCs, understand...

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Главные авторы: Sturgeon, Christopher M., Ditadi, Andrea, Awong, Geneve, Kennedy, Marion, Keller, Gordon
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152856/
https://ncbi.nlm.nih.gov/pubmed/24837661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2915
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