Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells

Induced pluripotent stem cells (iPSCs) stand to revolutionize the way we study human development, model disease, and eventually, treat patients. However, these cell sources produce progeny that retain embryonic and/or fetal characteristics. The failure to mature to definitive, adult‐type cells is a...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Leung, Amy, Zulick, Elizabeth, Skvir, Nicholas, Vanuytsel, Kim, Morrison, Tasha A., Naing, Zaw Htut, Wang, Zhongyan, Dai, Yan, Chui, David H. K., Steinberg, Martin H., Sherr, David H., Murphy, George J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099224/
https://ncbi.nlm.nih.gov/pubmed/29569827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2822
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