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Wnt Signaling Controls the Specification of Definitive and Primitive Hematopoiesis From Human Pluripotent Stem Cells

Efforts to derive hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) are complicated by the fact that embryonic hematopoiesis consists of two programs, primitive and definitive, that differ in developmental potential. As only definitive hematopoiesis generates HSCs, understand...

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Detalhes bibliográficos
Main Authors: Sturgeon, Christopher M., Ditadi, Andrea, Awong, Geneve, Kennedy, Marion, Keller, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152856/
https://ncbi.nlm.nih.gov/pubmed/24837661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2915
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