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WWOX At The Crossroads Of Cancer, Metabolic Syndrome Related Traits And CNS Pathologies

WWOX was cloned as a putative tumor suppressor gene mapping to chromosomal fragile site FRA16D. Deletions affecting WWOX accompanied by loss of expression are frequent in various epithelial cancers. Translocations and deletions affecting WWOX are also common in multiple myeloma and are associated wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aldaz, C. Marcelo, Ferguson, Brent W., Abba, Martin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151823/
https://ncbi.nlm.nih.gov/pubmed/24932569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2014.06.001
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