EFA6 controls Arf1 and Arf6 activation through a negative feedback loop

Guanine nucleotide exchange factors (GEFs) of the exchange factor for Arf6 (EFA6), brefeldin A-resistant Arf guanine nucleotide exchange factor (BRAG), and cytohesin subfamilies activate small GTPases of the Arf family in endocytic events. These ArfGEFs carry a pleckstrin homology (PH) domain in tan...

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Main Authors: Padovani, Dominique, Folly-Klan, Marcia, Labarde, Audrey, Boulakirba, Sonia, Campanacci, Valérie, Franco, Michel, Zeghouf, Mahel, Cherfils, Jacqueline
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151748/
https://ncbi.nlm.nih.gov/pubmed/25114232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409832111
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