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EFA6 controls Arf1 and Arf6 activation through a negative feedback loop
Guanine nucleotide exchange factors (GEFs) of the exchange factor for Arf6 (EFA6), brefeldin A-resistant Arf guanine nucleotide exchange factor (BRAG), and cytohesin subfamilies activate small GTPases of the Arf family in endocytic events. These ArfGEFs carry a pleckstrin homology (PH) domain in tan...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151748/ https://ncbi.nlm.nih.gov/pubmed/25114232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409832111 |
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