Murine CD27((−)) Vγ6((+)) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages

Cancer-associated inflammation mobilizes a variety of leukocyte populations that can inhibit or enhance tumor cell growth in situ. These subsets include γδ T cells, which can infiltrate tumors and typically provide large amounts of antitumor cytokines, such as IFN-γ. By contrast, we report here that...

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Detalhes bibliográficos
Main Authors: Rei, Margarida, Gonçalves-Sousa, Natacha, Lança, Telma, Thompson, Richard G., Mensurado, Sofia, Balkwill, Frances R., Kulbe, Hagen, Pennington, Daniel J., Silva-Santos, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151711/
https://ncbi.nlm.nih.gov/pubmed/25114209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403424111
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