Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress

Interleukin 17 (IL-17)–producing γδ T cells (γδ17 T cells) have been recently found to promote tumor growth and metastasis formation. How such γδ17 T-cell responses may be regulated in the tumor microenvironment remains, however, largely unknown. Here, we report that tumor-associated neutrophils can...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Mensurado, Sofia, Rei, Margarida, Lança, Telma, Ioannou, Marianna, Gonçalves-Sousa, Natacha, Kubo, Hiroshi, Malissen, Marie, Papayannopoulos, Venizelos, Serre, Karine, Silva-Santos, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965901/
https://ncbi.nlm.nih.gov/pubmed/29750788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2004990
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