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Recruitment of γδ T lymphocytes to tumors: A new role for the pleiotropic chemokine CCL2

Despite the promise of targeting γδ T cells for cancer immunotherapy, the mechanisms underpinning the recruitment of this T-cell subsets to neoplastic lesions remain poorly understood. We have recently identified the pro-inflammatory chemokine CCL2 and its receptor CCR2 as key molecular determinants...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lança, Telma, Silva-Santos, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812202/
https://ncbi.nlm.nih.gov/pubmed/24179705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25461
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