γδ-T cells promote IFN-γ–dependent Plasmodium pathogenesis upon liver-stage infection

Cerebral malaria (CM) is a major cause of death due to Plasmodium infection. Both parasite and host factors contribute to the onset of CM, but the precise cellular and molecular mechanisms that contribute to its pathogenesis remain poorly characterized. Unlike conventional αβ-T cells, previous studi...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Ribot, Julie C., Neres, Rita, Zuzarte-Luís, Vanessa, Gomes, Anita Q., Mancio-Silva, Liliana, Mensurado, Sofia, Pinto-Neves, Daniel, Santos, Miguel M., Carvalho, Tânia, Landry, Jonathan J. M., Rolo, Eva A., Malik, Ankita, Silva, Daniel Varón, Mota, Maria M., Silva-Santos, Bruno, Pamplona, Ana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2019
Onderwerpen:
PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525508/
https://ncbi.nlm.nih.gov/pubmed/31028144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814440116
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