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DNA Ligase IV regulates XRCC4 nuclear localization
DNA Ligase IV, along with its interacting partner XRCC4, are essential for repairing DNA double strand breaks by non-homologous end joining (NHEJ). Together, they complete the final ligation step resolving the DNA break. Ligase IV is regulated by XRCC4 and XLF. However, the mechanism(s) by which Lig...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151352/ https://ncbi.nlm.nih.gov/pubmed/24984242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.05.010 |
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