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Werner Protein Cooperates with the XRCC4-DNA Ligase IV Complex in End-Processing

Werner syndrome is a rare human disease characterized by the premature onset of aging-associated pathologies, cancer predisposition, and genomic instability. The Werner protein (WRN), which is defective in Werner syndrome (WS) patients, belongs to the RecQ family helicases and interacts with several...

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Detalhes bibliográficos
Main Authors: Kusumoto, Rika, Dawut, Lala, Marchetti, Caterina, Lee, Jae Wan, Vindigni, Alessandro, Ramsden, Dale, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572716/
https://ncbi.nlm.nih.gov/pubmed/18558713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702325t
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