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PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding
Activation of central PPARγ promotes food intake and body weight gain; however, the identity of the neurons that express PPARγ and mediate the effect of this nuclear receptor on energy homeostasis is unknown. Here, we determined that selective ablation of PPARγ in murine proopiomelanocortin (POMC) n...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151211/ https://ncbi.nlm.nih.gov/pubmed/25083994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76220 |
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