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Ablation of PPARγ in subcutaneous fat exacerbates age‐associated obesity and metabolic decline

It is well established that aging is associated with metabolic dysfunction such as increased adiposity and impaired energy dissipation; however, the transcriptional mechanisms regulating energy balance during late life stages have not yet been fully elucidated. Here, we show that ablation of the nuc...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Xu, Lingyan, Ma, Xinran, Verma, Narendra Kumar, Wang, Dongmei, Gavrilova, Oksana, Proia, Richard L., Finkel, Toren, Mueller, Elisabetta
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847881/
https://ncbi.nlm.nih.gov/pubmed/29383825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12721
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