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Ablation of PPARγ in subcutaneous fat exacerbates age‐associated obesity and metabolic decline

It is well established that aging is associated with metabolic dysfunction such as increased adiposity and impaired energy dissipation; however, the transcriptional mechanisms regulating energy balance during late life stages have not yet been fully elucidated. Here, we show that ablation of the nuc...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Xu, Lingyan, Ma, Xinran, Verma, Narendra Kumar, Wang, Dongmei, Gavrilova, Oksana, Proia, Richard L., Finkel, Toren, Mueller, Elisabetta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847881/
https://ncbi.nlm.nih.gov/pubmed/29383825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12721
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