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PPARγ signaling exacerbates mammary gland tumor development

Breast cancer cell lines that express the nuclear peroxisome proliferator-activated receptor γ (PPARγ) can be prompted to undergo growth arrest and differentiation when treated with synthetic PPARγ ligands. To evaluate the therapeutic potential of increased PPARγ signaling in vivo, we generated tran...

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Detalhes bibliográficos
Main Authors: Saez, Enrique, Rosenfeld, John, Livolsi, Antonia, Olson, Peter, Lombardo, Eleuterio, Nelson, Michael, Banayo, Ester, Cardiff, Robert D., Izpisua-Belmonte, Juan Carlos, Evans, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC374235/
https://ncbi.nlm.nih.gov/pubmed/15037548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1167804
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