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Integrated control of appetite and fat metabolism by the leptin-proopiomelanocortin pathway
Leptin deficiency results in a complex obesity phenotype comprising both hyperphagia and lowered metabolism. The hyperphagia results, at least in part, from the absence of induction by leptin of melanocyte stimulating hormone (MSH) secretion in the hypothalamus; the MSH normally then binds to melano...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31208/ https://ncbi.nlm.nih.gov/pubmed/11259669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071054298 |
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