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Integration of Endocannabinoid and Leptin Signaling in an Appetite-Related Neural Circuit

Recently developed therapeutics for obesity, targeted against cannabinoid receptors, result in decreased appetite and sustained weight loss. Prior studies have demonstrated CB1 receptors (CB1Rs) and leptin modulation of cannabinoid synthesis in hypothalamic neurons. Here, we show that depolarization...

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Detalhes bibliográficos
Main Authors: Jo, Young-Hwan, Chen, Ying-Jiun J., Chua, Streamson C., Talmage, David A., Role, Lorna W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2280039/
https://ncbi.nlm.nih.gov/pubmed/16364907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2005.10.021
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