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Successful Construction and Massive Expression of a Novel Anti-CD19 Human-Mouse Chimeric Antibody Hm2E8b

CD19 antigen is a major target for human B cell malignancies. Many studies have shown that the antibodies recognizing this antigen hold clinical therapeutic potential, while CD19 antibody of mouse origin requires genetic engineering to reduce the potential side effects of the antibody for their clin...

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Detalhes bibliográficos
Main Authors: Shen, Diying, Tang, Yongmin, Li, Sisi, Xu, Weiqun, Zhang, Lingyan
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151071/
https://ncbi.nlm.nih.gov/pubmed/25171000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2013.0079
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