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Pharmacokinetics and tolerability of human mouse chimeric anti-CD22 monoclonal antibody in Chinese patients with CD22-positive non-Hodgkin lymphoma

The safety and pharmacokinetics assessment of antibodies targeting CD22 (e.g., epratuzumab) have been established in western Caucasian populations, but there are no reports of the effects in Chinese populations. This dose-escalation study examines the safety, pharmacokinetics and biologic effects of...

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Detalhes bibliográficos
Main Authors: Li, Su, Zhang, Dongsheng, Sun, Jian, Li, Zhinming, Deng, Liting, Zou, Benyan, Zhan, Jing, Jiang, Wenqi
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361661/
https://ncbi.nlm.nih.gov/pubmed/22453099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.4.2.19136
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